Case

Allosteric Target Discovery Engine

Challenge

Which of the 20,000+ potential protein drug targets
are most promising for allosteric control?

Solution

Rapid triangulation of the target space by connecting sequence, structure and mechanism data using AI.

Impact

Two targets in Lead Optimization plus more in the pipeline (as of 9/2021).

Client

HotSpot Therapeutics is a Boston-based biotech company targeting nature’s regulatory mechanisms to create new allosteric medicines that exhibit high precision and potency.