While etiology and pathophysiology of most diseases are still poorly understood, there has never been a better time to fix this: Thore Bürgel (Pheiron) explains how they combine human genetics with multi-modal AI to resolve disease pathology, identify targets, and de-risk translation.

AlphaFold has been called a revolution for drug discovery. Here we discuss potential use cases of AlphaFold, from fostering disease understanding, to aiding structural drug discovery.